Microfluidics Applications and Chips

PDMS Drop-seq chip

Drop-seq chip is a PDMS Chip containing 22 operational designs including a Silane hydrophobic coating.

High throughput results in a short period of time
Minimize consumption of expensive samples
Prepare a single-cell suspension from a tissue
Analyzes sequences of single cells in a highly parallel manner
Unique molecular and cell barcodes enable cell- and gene-specific identification of mRNA strands
RT with template-switching PCR produces high-yield reads from single cells

EZ drop

The Droplet Kit is designed to be used with the Droplet Starter Pack. It contains the PDMS Droplet Chips with tubing and fittings needed for your experiment. It works with any Flow EZ™ pressure channels and FLOW UNITS models.

RayDrop Double Emulsion

The RayDrop is a microfluidic double emulsion device composed of three main, fully removable parts: two inserts on each side,a center section containing a nozzle, and an outlet capillary. There are 5 standard microfluidic connections, two on the box for the continuous phase and three others: one on each insert for the core shell phase entry,and one on the collecting emulsion outlet. The droplets are produced by controlling the squeezing of the droplet phase locally generated by the continuous phase at the entrance of the collection capillary.

The RayDrop specific design allows for multiple liquid type emulsification within the same device with no coating needed. The device can create both single and complex emulsions.

RayDrop SINGLE Emulsion

The RayDrop Single Emulsion Device is a microfluidic droplet generator composed of three main fully removable parts: two inserts on each side, a center section containing a nozzle, and an outlet capillary. There are four standard microfluidic connections, two on the box for the continuous phase, one on each insert for the dispersed phase entry, and one on the collecting emulsion outlet.

The RayDrop Single Emulsion Device’s specific design allows for multiple liquid type emulsification within the same device without any coating needed. This allows users to cover single and complex emulsions.

Applications from encapsulation of active pharmaceutical ingredient (in both polymer microparticle) to cell and fragrance encapsulation in hydrogel microbeads are covered, such as:

PLGA microparticle
Alginate microbeads
Liposome Nanoparticle

RayDrop SINGLE Emulsion

BE-Flow is Beonchip’s most easy-to-use device dedicated to cell culture under flow. It allows the performance of long-term 2D or 3D culture in two independent channels. BE-Flow is compatible with any microfluidic pump system and can be used simply with a rocker, thanks to its fluid reservoirs situated by the inlets/outlets. This is an optimal device for vascular research where shear stress plays a major role in gene expression.

FCS2 Chamber

The Focht Chamber System 2 (FCS2®) is a closed system, live-cell micro-observation chamber that utilized several patented technologies that offer several exclusive advantages over other chambers. In addition to its uniform temperature control and user-definable perfusion capability, it is fully compatible with all modes of microscopy. The chamber is adaptable to the protocol instead of having to adapt the protocol to the chamber.

BE-DoubleFlow

BE-Doubleflow is Beonchip’s most advanced device. It consists of two perfusable channels connected via a porous membrane. Explore the crosstalk between different 2D and 3D cultures in a biomimetic environment and control the efficiency of the interaction by selecting the optimal pore size for your application. This is the optimal device when a hypoxia environment is needed, for studying the effect of circulating particles (bacteria, immune system, circulating tumor cells) and for endothelium/epithelium barrier when no ALI is needed or when flux plays a role in both sides of the coculture.

BE-Gradient

Designed for the application of electrochemical gradients to 3D cell cultures.

BE-Gradient is Beonchip’s device designed for the application of electrochemical gradients to 3D cell cultures. BE-Gradient is compatiblewith any type of optical microscopy (inverted phase contrast, confocal, fluorescence..). Be-Gradient consists of a central chamber for cell culture and two lateral channels connecting to the central chamber through 3 small microchannels. Lateral channels are meant to simulate blood vessels. 2D culture is also possible for adherent cells not only in the central chamber but also in the lateral channels.

BE-Transflow

BE-Transflow is Beonchip’s most versatile cell culture platform. It allows the study of complex culture configurations by joining a culture well with a microfluidic channel via a porous membrane. This is the optimal device for Air Liquid Interface (ALI) culture, endothelium/epithelium barrier and crosstalk studies.

CONTACT OUR SPECIALIST